The client who has sickle cell trait has a sister with sickle cell disease and a husband with neither the disease nor the trait. She asks her nurse what her children’s chances are of having sickle cell disease. What is the nurse’s best response?
“Because your sister actually has sickle cell disease, the risk for your children having sickle cell disease is 50\% with each pregnancy.”
“Because you are a woman, your daughters will each have a 50\% risk for having the disease and all of your sons will be carriers of the trait.”
“Because you have the trait and your husband does not, none of your children will have the disease, but each child will have a 50\% risk for having the trait.”
“Because you have the trait and your husband does not, only your daughters can have sickle cell disease.”